Cabgolin (Cabergoline)

Product description

Cabgolin has a good applicability in treatments of disorders characterized by elevated levels/secretion of prolactin. Such a condition often develops as the body’s response to tumors growing in the pituitary gland or certain causes yet unknown to medicine. The main active substance of this drug is Cabergoline.

This active substance is an ergot-derived agonist of the dopamine D2-like receptors. It also demonstrates high affinity towards D2, D3, as well as 5-HT2B receptors. However, it is mostly its potent D2 receptor affinity that finds use in clinical practice, namely in dopamine replacement therapies of Parkinson disease, Cushing’s disease, ovarian hyperstimulation syndrome, hyperprolactinemia, and restless legs syndrome. Due to the greater elimination half-life of cabergoline (63-109 hours), it wins the comparison with other agonists of D2-like receptors. Its strong properties ensure a long-lasting therapeutic effect when applied in single-dose administrations and an overall improvement in the patients’ quality of life in cases of chronic and persistent diseases.

Important warnings and precautions

Cabgolin may lead to drowsiness, giddiness, or fainting. These undesirable effects may worsen if the drug is used along with alcohol or incompatible medicines. Exercise special caution when staying on the medicine. Exclude engaging in unsafe tasks such as driving or operating industrial machinery until you learn your exact reaction to this pharmaceutical product. If any of the above effects take place, try to sit up or lie down. This may help you stop the unpleasant symptoms from continuing.

Certain categories of patients staying on Cabgolin have experienced changes in behavior (for instance, potentiated gambling urges or increased sexual desire). These effects normally do not last when the drug treatment comes to a stop. Call your doctor if your behavior changes in a way that troubles you.

Cabgolin should be stored at usual room temperature (68-77 °F), in a well-sealed container (preferably, the original package). Keep it protected from heat, high humidity, and direct light. A bathroom cabinet should not be considered a suitable storage place. Ensure that your children and pets cannot reach the drug container/package.

Safety information

Certain medical issues and conditions may pose a risk of interaction with Cabgolin:

• distinct signs of allergies to this medicine, other pharmaceutical substances, and foods;
• ongoing pregnancy, intended pregnancy, or nursing an infant. If you have a reason to think you may be pregnant, visit your primary care doctor to conduct a pregnancy test;
• certain clinical issues caused by or connected to pregnancy (for instance, elevated blood pressure, convulsions);
• ongoing treatment with any prescribed or non-prescribed medication, herbages, or biological supplements;
• existing problems with the liver or abnormal blood pressure, or if you are staying on antihypertensives.

Inform your pharmacist or doctor of any of your past and current medical conditions, as well as medicines you would like to co-administer with this one.

Side effects

You face only a minor risk of side effects with Cabgolin, most of which may pass quickly. However, visit a doctor to resolve the following ones if they persist:

constipation, faintness, headaches, unsettled stomach, tiredness or weakness, nausea, vomiting.

Read the product’s leaflet on a complete list of all the possible adverse events.